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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306ce613c8f9eb69a13027fc24fb66bf9894a9ebed69c265187b7c924466aeb3' 
  AND token = 'FQodpnRLipNC0fH18Kvh8VPK7w+w86B2qX4I6ihDh5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}