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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82d68c21914603da94cac91edceeb67e9e9c6b21fcb09f21bf96de5a67b729e0' 
  AND token = '6kqs8YjCVDNoXVM8dn+XbDBANhbiLMRx0QJq6T44Nj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}