SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57cb9ad905f937efc7ccd6ceaa3d65a6e0390f82798868f5509c916937d56aa' 
  AND token = '0hUmTd/TFS2EF2tyKd+n5sOHlR1DIROJluBPvZZjLgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}