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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee572c3bd981941b47add94c3e27320e93a43cfc4fd74d6d9d121884472a34b2' 
  AND token = 'T2Sp0juddZ3R0l2iPidTTPNiLG6zNBgi8UdlJodmOmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}