SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d31c641df607f8d6272803c91d635c6fa0c85a035be0b663a54aa0f8c0654b0' 
  AND token = '4Iy9ac+SJ4WwFMOxMPDQwcwmHFSpmKIoMTmmOQIKNTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}