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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fdb265e04ec7698b5960966fe401a37b96b1315320722b979c5db6ea0eee816' 
  AND token = '64N5e3IPEr515zKMJpPBvlMPWzIY+xRudm0c6xGgOdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}