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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa80605cf6ecf44946e10256e108946eef658f51bf274a102efc51304d02a267' 
  AND token = 'G5vEit1yic0auyMbSWTgbjF2BKbyoONjdYcWu+rimsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}