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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0acafe1f7c68291ecf575c568ea5547455143b8e448f4d2bcf3e7db38cdeed4f' 
  AND token = 'Qf4De4UNLNEZARe8UC3OpNS5i3SVtyYUlHiKLl4poTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}