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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54778b63f5b8baaf9ad52dbc4afec31bd47d39b4a0eeb5b9efb8b8a52fa6402c' 
  AND token = 'BnYbDNi+puTMedAh7qmUuebOAXV4GbMUneZ36lrxJwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}