SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c771a7de76790ec3a61494c35adf2fdd451a3c4cdf639e685cdd2daab09671cb' 
  AND token = 'FsrsFmdWGWPTqYZ5Ycmf+fEt+RvfMPFvZEaMH61FW2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}