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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2684d06063833a24a1b47962d8e2c635994a44b46be1ca5104ad530df077858' 
  AND token = 'NMhh2vJhQZ4kE4rKvbK4RiwKSEAhq6X5SWt/mS2Ogys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}