SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356192d892b50ba5bc0ff842365db1157398a13a90f7cd87a1644eb9edafa49c' 
  AND token = 'aKIUC5B92ljoCnoZ8b5ZGjrfqzHwPfcni98Ms94Rp0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}