SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e31660c414a73e6a23f176fa667758568ffb74a7c2ff10815ef865997c59207f' 
  AND token = '1xqXmUA7F4Ynzwgjjr12bgjpo6sBRwJm9jedaA8XuJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}