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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16891106769366a43dd955c6b5e3640b3f49e2a6b0cad6f72a59fc4e0f5b8dda' 
  AND token = '44aVJbxkYhBVXB6TqEzn0KsYfkV/23LJ4efauY0ht3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}