SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbb912c744ac8137292150674966dd2b49e541b010fb89d0a9fa303d77a24eb6' 
  AND token = 'HYXsrnYnPRM4OtVuwMenFyCoZj21krPKhRwznsxR3hM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}