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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cc46b3d2a0464457356e0205af50d85159eb516ad0232567816ed30d00729a' 
  AND token = 'gpK6KXqYcffK4i/lDQ8KUNTuOjZHK0pZbuiQlJfhB4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}