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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20521851d91fe9ee56ed4fda8aef78f8a7a07c7affdbcde61e58f8c0f652bf47' 
  AND token = 'pzmB3QhzBo76L+lFcsPpsKf7EVKQNQNGdcrSdZSLo7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}