SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b076d2d4d4ca3ec068568655a7a1f56fc8c1f86c7109b46332b4de4bb3b0f68' 
  AND token = 'gEXAgBqvDk1RxojRMZNiNbvd2DUbtNxatiAtZ2aJ+WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}