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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33246ae577a0f5cbb84e24fe1deb87e9177043ee487fea9f0d8ba490f6643037' 
  AND token = 'USBmhvziDe854eMqEcO4f2ojbkKfjecjc9T1R+z/coI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}