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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421af2d98e0bf5a0e473d376f83aba33340bb7ec6a989abd88183e9086e852d1' 
  AND token = 'toPq3S36OGe59qtf3tXet0A0SvB86GVfQ3jGg4jv5z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}