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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abc59a21267388df255bd0fce06d7c4927ba83021e984217ff6f850bde144d4' 
  AND token = '5mR61c3FBSAGEKjFFfcNAnhR+Vk2c/he67ssk8XK8Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}