SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2209457ec0a396c4dfc4ff104297319d8ae877f789241cb2788b6bcebd0a515' 
  AND token = 'IT5T1lH3pSzCBTcClaMLHA3/YXXuvA4m3pQCJb8Tn8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}