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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd274f65937433e72fef4c95e88f90473b37aaa88b8bedfd8f42f686b750e62b6' 
  AND token = '0xOBo27EM/LQ3W+WEG5MB/JxZfWHhnJvZLVvDfr2Vr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}