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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e54461b1367a3e85880f0cf2f23994ac848fd031ad75124f03af5ac1b34648' 
  AND token = '+zzy4A5bLy/RvIy9uzf/YdsT1QukC01fVXzUNnZrWCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}