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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528963e72a3c81a17b5863c2fcf3bc9b50a24b85096488db470a4963b8df96dc' 
  AND token = 'V/6hRGPH6GFPobE/ECFgNcjIECFVmPX4cXW1t6e7st4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}