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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c152cb7f012b3762dd4c2de676efb8de72c92a55f34e3ae540e80d2f2e7d07' 
  AND token = 'UpOpLsUl8W9gTvl8bCtRGnILFEIfKi1rft2hJR/Aal0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}