SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df9272e086a2501bdc6668dd68aea8f0046b90bc1dd5e86cf61bb7bd79fb8600' 
  AND token = '8wWZQFw9CiwPU9AT4SzagssIcxcqf3P6MPaiWLBzIYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}