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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81653c8ae8e5795622fcd76a9abb06d8b534d61722c7e8b81a2486c66993b1b9' 
  AND token = 'aq/8nP8uA7pD7m/GE1BIeMIqg3/7Vw8AKaRB5wiVjPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}