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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c0da2eacaf6174d1cbfed4059cf4912c3072caaa2cd09cbc2595c3e2a719b9' 
  AND token = 'EFvQESnAq03NNyx8TPBfIEztzm4lfcT/5mTlQPKSMSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}