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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaa0583c6deba2791830a8672a7566338d0d9c5200d474931d37d263242e2efc' 
  AND token = 'nxKo1PTuKLWAYRbpvrDJN6RjcNDlQ795im5D4OT5BkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}