SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14099774217f32b72d91cfffd8e128397303900fa9bf43f8cd36ef4691371cc7' 
  AND token = 'dqY3rZOYqfkyxB+Rppl1LKTYjb2F1KM19Qr+bxYJ8F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}