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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757d4f10b789f0a53d4a96c30cc41e85e21d22911c6595406257ea5682a64048' 
  AND token = 'XO1C5nabWC4JBEEHdkNKw1+8QSsVgMiExSR7pU93sKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}