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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a70f619d5c4cc482f36ef84efa2349c4b44a2212d018812df7b618f044cea52' 
  AND token = 'yXaGno+Du+B8FcRNIcBYpOFvVyKIEDzUyli1AF6Sgbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}