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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f192d1e9f445f84ff27d77401d0fa5264297cc351bcb10422c5b8bc108d0e86f' 
  AND token = 'DG/01VVgerrcU/C4rwJwtzGf32tVVtulM/2PCc9nbpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}