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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4279d52afb4d20647fb105c2bc23e7c6f75a4f4bb48b9078ca17d53fe048a65' 
  AND token = 'knJH+0jRLmQs/0XSNUTXHKOxXXb+BskWvXUhRSrbxBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}