SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09bd327e9571e25ee01333e3bf28cc3dada0f8148130f787b5f7c4d3205d6a38' 
  AND token = 'vPJmqWwSmF1ctWxtASwWBajM/d8jSmCVqQyO5WygWyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}