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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22eb3c9d07003eb6329cff4ecc5691fd039c2fb43926b302fa4e247e394d40e' 
  AND token = 'cEt4VckRK+9Y1Q4drUZKip7DDJLQQi9P2gKBJ1wzOSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}