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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df27c26cedba8f3f2d29573b873cfbd0352c56b3d4dca6679179c4fdd3b37037' 
  AND token = 'EGcc+XwYuSnV3ak5wm3UXdPhYUlhfO1SkY5HFP5MZ/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}