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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f914f89cae69f3669b8d66bfc66adc822adc3ab79b78d3c411df1ad21ac2ad' 
  AND token = 'FL9jyamO6QkYZ/0A2S+B+bKGmXQ9PTXLnGSsEJZvEAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}