SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d4347fbdf82371cd597352f0b0792abe38afaafdb82ae76e17a852509db844' 
  AND token = 'iOobsE4zPtiX+t4eLRKXOkOnmEj9rlnNL7dsd1PzxMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}