SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e31f22c8e34360fd2fed96cabf3ff3e7eeca09fb7d894b27985b2fccea4b17' 
  AND token = '2SPE0Q89elSh21FJqLgVttq3Rr1X06CPm5k9d8Dm81E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}