SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a7c7a364437958ca7e24d4119515ad210750174383d4b5bc4a998aa3b03998' 
  AND token = 'f2Vu3/9qzLovV6RpPnH8G36IIYiMBfZt+FRE4B4IMS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}