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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6106d761f99e681f13cb88121f2fa23aee37af441465dc3d34b8acfc9f4f7522' 
  AND token = 'j+8kcgaxgx+jc8YAuxRd1UsL6im01MjubBbG8vVUCCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}