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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '591d68ea9153052ed29ae5dd25e588cf438e7ced6b1cf0d56a03c676cde0f598' 
  AND token = 'wtdLhxuuXmZVQRgogcwfJedAr6v0XUjwy+cQ6kYFFos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}