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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e816fb0171ac2fa23bd6db7e601d2f4b0ce1c4d81336d82b36a453402b1ad60' 
  AND token = '1p1CnxBF2AvYZdYHKEc3aiff6NOKyUkTk/UTG2KVgZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}