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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e9e4d74bf4947473bb8a375a54ec19017ecc13233cb519d1d081505eb688a8' 
  AND token = 'iC3EFCYi+ct7Wp5AdF2+2SyGrt+uxt4KS5D83ZOS+hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}