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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a12fd70b8c12ef1cba763439e23b0d74cf8631c5c56c2b0c681cc97348ab086' 
  AND token = 'MM0dA+JYzrXLLRbRkEncnJgZjyCvOa/uw+Asdus/f48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}