SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42532b61e862ecb3301532336067e9c65c65cf97a173902ab2dc351cd9c0b11' 
  AND token = 'V5u22JCcINwNKUf5uzyBU1hSVCQGMbrj3COkzY17Al0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}