SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9169536ed64eb874ea72dbc362d71d22b560c3ee5e2fcc405a5ad11f7bbf5b8' 
  AND token = '6wNEmMkWTpEDdsKyD/RS1wls4DFDl8FCKwhYZGnIt1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}