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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65504f08fc4f1f7cbe859cb75081a0db5dc9eeeae956da97f84a9c25dae8a1f6' 
  AND token = 'VSnYT2WnNp6hpw4sOrwJW9+CfHY4gpJhRwro0YHaLEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}